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用来对抗脱发的牛磺酸

[日期:2013-07-22] 来源:網路轉載  作者:站長 [字体: ]

大家有喝 过电视上广告,‘喝了在上...康贝特’,或是赞助赛车不遗余力的红牛(Red bull)饮料,或是在日本已销售了50年,销售量达200亿瓶以上的リポビタン(力保美达)?这些在世界各地流行的机能性饮料中的主要成分牛磺酸 Taurine,可是有对抗脱发的潜力呢!

 
牛磺酸(Taurine) 是一种带有氨基的磺酸(不是胺基酸),是身体所需营养成分之一,被指为对婴儿脑部及眼部发展有良好影响,而被放入奶粉的成份里面。牛磺酸在维持脑部运作及 发展方面都扮演着重要的角色。牛磺酸能加速神经元的增生以及延长的作用。由于牛磺酸有抑制神经的作用,所以它亦有抗痉挛及减少焦虑的特点。牛磺酸同时具有 抗氧化的特点,故此它亦能保护脑部免受氧化物的伤害。(以上这段出自Wikipedia)

研究摘要整理:

脱发或秃发被视为一种文明病,在面临各种压力的状况下,有可能加重脱发的症状。脱发症也由好发在40~50岁的年纪,转变成现今普遍在20~30岁的年纪就会发生。

研究指出,与其他市售抗脱发产品作比较,牛磺酸是有潜力对抗化学性压力(chemical stress)脱发的,所谓的化学性压力,指的是我们身边可能遇到的各种化学污染源,如空气、用水、药物、不健康食物、食品添加物,或是如烟、酒、咖啡因饮料等其它化学成份之食品。

研究使用 秀丽隐杆线虫(Caenorhabditis elegans),秀丽隐杆线虫是一种可以独立生存的线虫,长度约1公厘,生活在温度恒定的环境。秀丽隐杆线虫可做为模式生物,以研究发育生物学及神经科 学。所采用的标准为他们在应对压力的表现,及生命征象(Vital signs)变化测量的影响:寿命比较、后代数量和迁移率。

线虫显 示,如果施以衣霉素(tunicamycin),会出现典型压力症状,线虫的寿命和其后代的数量显著下降,并伴随着不同寻常的迟缓运动。有趣的是,当蠕虫 以牛磺酸、astressin-B和Finasteride(柔沛成分)一同治疗,却显示了正向反应。在治疗期间,Finasteride在降低压力效果 上显示更好的结果,牛磺酸更有效地帮助蠕虫由压力的不利影响中恢复。

研究结论指出,有强力的证据显示,牛磺酸用来对抗脱发有很大的潜力,尤其是对化学性压力的不利影响。牛磺酸如果结合其他对抗脱发的产品,也许会有很强的效果。



如果我们想补充牛磺酸,有相关的产品吗?除了上述耳熟能详的机能饮料,其实法国L'OREAL有一款针对对抗脱发的口服锭,Inneov Hair Mass Supplements,当中就有牛磺酸等成分,有小规模临床实验。当然,也有单一牛磺酸成分的补充品,剂量较高,且品牌众多!! 该如何定位这成分?如果非雄性秃,与化学性压力有关的脱发,再考虑尝试。

研究原文:

Adv Exp Med Biol. 2013;776:267-76. doi: 10.1007/978-1-4614-6093-0_25.
Simulative evaluation of taurine against alopecia caused by stress in Caenorhabditis elegans.
Kim H, Chang H, Lee DH.
Source Department of Life Sciences, University of Seoul, Seoul, South Korea. (韩国首尔大学)

Abstract
Hair loss or alopecia has been portrayed as a modern malady which is aggravated by stressful conditions. Major cases of alopecia were found among individuals of 40s-50s, nowadays, even among the 20s-30s. This study characterized taurine's potential against alopecia caused by chemical stress agents based on the comparison with other commercially available anti-alopecia agents using Caenorhabditis elegans. The criteria used are their effects on the expression of stress markers and measurements of vital signs: lifespan comparison, progeny number, and mobility. C. elegans showed the typical stress symptoms under treatment with tunicamycin, endoplasmic reticulum stress agent. Hsp-70 protein expression increased, while worm's lifespan and per capita progeny number significantly decreased along with an unusually retarded movement. A positive response was shown when worms were treated with taurine along with astressin-B and finasteride. Between the treatments, finasteride showed better outcomes in terms of stress-reducing effects. Taurine helped worms recover more effectively from adverse influence of stress. In conclusion, there is strong evidence that taurine has a great potential as anti-alopecia effect especially against the one caused by the chemical stress. The present study implies that taurine might strongly work against hair loss when used in combination with other commercially available -anti-alopecia agents.

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